Intermolecular interactions of benzimidazole derivatives
نویسندگان
چکیده
منابع مشابه
Effects of Benzimidazole derivatives on digestive system and cardiovascular system
One of the goals of medicinal chemistry research and drug discovery is to provide a rationalbasis for the design of new medicinal agents. Organic compounds and their reactions have beenutilized by people since antiquity. Due to the increasing demand for bioactive molecules, organicchemists are increasingly required to synthesize new compounds of biological interest. AsBenzimidazoles are very us...
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Conformational fluctuations of a protein molecule are important to its function, and it is known that environmental molecules, such as water molecules, ions, and ligand molecules, significantly affect the function by changing the conformational fluctuations. However, it is difficult to systematically understand the role of environmental molecules because intermolecular interactions related to t...
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To study the influence of intraand intermolecular interactions on properties of the nitro group in para-substituted nitrobenzene derivatives, two sources of data were used: (i) Cambridge Structural Database and (ii) quantum chemistry modeling. In the latter case, “pure” intramolecular interactions were simulated by gradual rotation of the nitro group in para-nitroaniline, whereas H-bond formati...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations and Advances
سال: 2015
ISSN: 2053-2733
DOI: 10.1107/s2053273315093109